Top Ten Articles 2017

  1. Blauvelt, A., et al. Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trialLancet. 2017;389(10086): 2287-2303.
  2. Ruzicka T, Hanifin JM, Furue M, et al. Anti-interleukin-31 receptor A antibody for atopic dermatitisN Engl J Med. 2017;376(9):826-835.3.
  3. Thijs JL, Strickland I, Bruijnzeel-Koomen C, et al. Moving toward endotypes in atopic dermatitis: identification of patient clusters based on serum biomarker analysisJ Allergy Clin Immunol. 2017;140(3):730-737.
  4. Guttman-Yassky E, Ungar B, Malik K, et al. Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitisJ Allergy Clin Immunol. 2017;140(4):1032-1042.e1013.
  5. Brunner PM, Suarez-Farinas M, He H, et al. The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteinsSci Rep. 2017;7(1):8707.
  6. Nakatsuji T, Chen TH, Narala S, et al. Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitisSci Transl Med. 2017;9(378).
  7. Williams MR, Gallo RL. Evidence that human skin microbiome dysbiosis promotes atopic dermatitisJ Invest Dermatol. 2017;137(12):2460-2461.
  8. Paternoster L, Savenije OEM, Heron J, et al. Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohortsJ Allergy Clin Immunol. 2018;141(3):964-971.
  9. Meylan P, Lang C, Mermoud S, et al. Skin colonization by Staphylococcus aureus precedes the clinical diagnosis of atopic dermatitis in infancyJ Invest Dermatol. 2017;137(12):2497-2504.
  10. Byrd AL, Deming C, Cassidy SKB, et al. Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitisSci Transl Med. 2017;9(397).


Other Important Articles in AD: Chosen by the International Eczema Council.

  1. Roduit C, Frei R, Depner M, et al. Phenotypes of atopic dermatitis depending on the timing of onset and progression in childhoodJAMA Pediatr. 2017;171(7):655-662.
  2. de Bruin-Weller M, Thaci D, Smith CH, et al. Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo-controlled, randomized phase III clinical trial (LIBERTY AD CAFE)Br J Dermatol. 2017.
  3. Brunner PM, Emerson RO, Tipton C, et al. Nonlesional atopic dermatitis skin shares similar T-cell clones with lesional tissuesAllergy. 2017;72(12):2017-2025.
  4. Heratizadeh A, Werfel T, Wollenberg A, et al. Effects of structured patient education in adults with atopic dermatitis: multicenter randomized controlled trialJ Allergy Clin Immunol. 2017;140(3):845-853.e843.
  5. Oetjen LK, Mack MR, Feng J, et al. Sensory neurons co-opt classical immune signaling pathways to mediate chronic itchCell. 2017;171(1):217-228.e213.
  6. Elias MS, Long HA, Newman CF, et al. Proteomic analysis of filaggrin deficiency identifies molecular signatures characteristic of atopic eczemaJ Allergy Clin Immunol. 2017;140(5):1299-1309.
  7. Tran MM, Lefebvre DL, Dharma C, et al. Predicting the atopic march: results from the Canadian Healthy Infant Longitudinal Development StudyJ Allergy Clin Immunol. 2018;141(2):601-607.e608.
  8. Boguniewicz M, Alexis AF, Beck LA, et al. Expert perspectives on management of moderate-to-severe atopic dermatitis: a multidisciplinary consensus addressing current and emerging therapiesJ Allergy Clin Immunol Pract. 2017;5(6):1519-1531.
  9. Schmitt J, Buske-Kirschbaum A, Tesch F, et al. Increased attention-deficit/hyperactivity symptoms in atopic dermatitis are associated with history of antihistamine useAllergy. 2018;73(3):615-626.
  10. Eckert L, Gupta S, Amand C, Gadkari A, Mahajan P, Gelfand JM. The burden of atopic dermatitis in US adults: health care resource utilization data from the 2013 National Health and Wellness SurveyJ Am Acad Dermatol. 2018;78(1):54-61.e51.
  11. Pols DHJ, Nielen MMJ, Bohnen AM, Korevaar JC, Bindels PJE. Atopic children and use of prescribed medication: a comprehensive study in general practicePloS One. 2017;12(8):e0182664.
  12. Ferreira MA, Vonk JM, Baurecht H, et al. Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biologyNat Genet. 2017;49(12):1752-1757.

Click on the ‘Abstract’ link for above-referenced articles on PubMed, along with copyright information.